As a disease of systemic inflammation psoriasis is associated with multiple comorbidities including cardiovascular disease and malignancy the diagnosis is primarily clinical and a skin biopsy is seldom required depending on the severity of disease appropriate treatment can be initiated for mild to moderate disease first line treatment involves topical therapies including corticosteroids vitamin d3 analogues and combination products these topical treatments are efficacious and can . Alcohol consumption may decrease the effectiveness of some psoriasis treatments if you have psoriasis avoid alcohol if you do drink use moderation strive to maintain a healthy lifestyle in addition to quitting smoking and drinking moderately if at all you can manage your psoriasis by being active eating well and maintaining a healthy weight. Conclusion many patients with psoriasis seek initial evaluation and treatment from their primary care providers recognition of psoriasis as well as its associated medical and psychiatric comorbidities would facilitate timely diagnosis and appropriate management with effective and safe topical therapies and other medical and psychological. Psoriasis diagnosis and management will provide dermatologists of all levels with a practical well illustrated approach to fully understanding the disease including clear clinical guidance to enable best practice and effective management of patients